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Dose evaluation of intravenous metamizole (dipyrone) in infants and children: a prospective population pharmacokinetic study

Published inEuropean Journal of Clinical Pharmacology, vol. 75, no. 11, p. 1491-1502
Publication date2019
Abstract

The prodrug metamizole is prescribed intravenously for postoperative pain in children, including off-label use in infants < 1 year. We aimed to assess the pharmacokinetics of the main metabolites of metamizole in children aged 3-72 months.

Keywords
  • Children
  • Dipyrone
  • Infants
  • Metamizole
  • Pharmacokinetics
Funding
  • Swiss National Science Foundation - 31003A_160216
Citation (ISO format)
ZIESENITZ, Victoria C et al. Dose evaluation of intravenous metamizole (dipyrone) in infants and children: a prospective population pharmacokinetic study. In: European Journal of Clinical Pharmacology, 2019, vol. 75, n° 11, p. 1491–1502. doi: 10.1007/s00228-019-02720-2
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Article (Published version)
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Identifiers
ISSN of the journal0031-6970
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Technical informations

Creation11/25/2019 2:37:00 PM
First validation11/25/2019 2:37:00 PM
Update time03/15/2023 6:27:46 PM
Status update03/15/2023 6:27:45 PM
Last indexation01/17/2024 8:20:08 AM
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