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Title

Variable ventilation is equally effective as conventional pressure control ventilation for optimizing lung function in a rabbit model of ARDS.

Authors
Danis, Judit
Published in Frontiers in physiology. 2019, vol. 10, 803
Abstract Introducing mathematically derived variability (MVV) into the otherwise monotonous conventional mechanical ventilation has been suggested to improve lung recruitment and gas exchange. Although the application of a ventilation pattern based on variations in physiological breathing (PVV) is beneficial for healthy lungs, its value in the presence of acute respiratory distress syndrome (ARDS) has not been characterized. We therefore aimed at comparing conventional pressure-controlled ventilation with (PCS) or without regular sighs (PCV) to MVV and PVV at two levels of positive end-expiratory pressure (PEEP) in a model of severe ARDS.
Identifiers
PMID: 31297064
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Structures
Research group Enfants et hyperréactivité bronchique (69)
Project
Swiss National Science Foundation: 32003B_169334
Citation
(ISO format)
FODOR, Gergely et al. Variable ventilation is equally effective as conventional pressure control ventilation for optimizing lung function in a rabbit model of ARDS. In: Frontiers in Physiology, 2019, vol. 10, p. 803. doi: 10.3389/fphys.2019.00803 https://archive-ouverte.unige.ch/unige:126047

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Deposited on : 2019-11-12

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