The IOF Compendium is an authoritative reference document on osteoporosis for all key stakeholders in the field of musculoskeletal health. It provides a concise overview of the pathophysiology, risk factors, prevention and management of the disease; documents the prevalence of osteoporosis and related fractures both globally and regionally; and outlines current research on the epidemiology, mortality, health expenditure, and access to/reimbursement for diagnosis and treatment for each region of the world.