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HIV-1 infection: going nuclear with TNPO3/Transportin-SR2 and integrase

Published in Current Biology. 2008, vol. 18, no. 16, p. R710-3
Abstract Factors necessary for HIV-1 nuclear import have been sought for many years. Recent reports suggest that TNPO3/Transportin-SR2 binds to HIV-1 integrase and is required for HIV-1 infection of interphase cells.
Keywords Cell Nucleus/metabolism/virologyHIV Integrase/metabolismHIV-1/metabolism/physiologyVirus ReplicationBeta Karyopherins/metabolism
PMID: 18727908
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Research group Réplication virale, pathogénèse et immunité (848)
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LUBAN, Jeremy. HIV-1 infection: going nuclear with TNPO3/Transportin-SR2 and integrase. In: Current Biology, 2008, vol. 18, n° 16, p. R710-3. https://archive-ouverte.unige.ch/unige:1249

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Deposited on : 2009-03-30

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