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Cellular circadian period length inversely correlates with HbA1c levels in individuals with type 2 diabetes |
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Authors | ![]() | |
Published in | Diabetologia. 2019, vol. 62, no. 8, p. 1453-1462 | |
Abstract | The circadian system plays an essential role in regulating the timing of human metabolism. Indeed, circadian misalignment is strongly associated with high rates of metabolic disorders. The properties of the circadian oscillator can be measured in cells cultured in vitro and these cellular rhythms are highly informative of the physiological circadian rhythm in vivo. We aimed to discover whether molecular properties of the circadian oscillator are altered as a result of type 2 diabetes. | |
Identifiers | PMID: 31134308 | |
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Structures |
Faculté de médecine / Section de médecine fondamentale / Département de médecine génétique et développement |
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Research groups | Education thérapeutique du patient, diabète et obésité (600) Endocrinologie et horloge circadienne (948) Nutrition clinique (597) | |
Project | Swiss National Science Foundation: Sinergia CRSII3_160741 | |
Citation (ISO format) | SINTUREL, Flore et al. Cellular circadian period length inversely correlates with HbA1c levels in individuals with type 2 diabetes. In: Diabetologia, 2019, vol. 62, n° 8, p. 1453-1462. doi: 10.1007/s00125-019-4907-0 https://archive-ouverte.unige.ch/unige:124844 |