This technical report describes 2 workflows for fabricating computer-aided design and computer-aided manufacturing (CAD-CAM) milled complete dentures (CDs). The first technique illustrates a manufacturer-independent workflow using conventional clinical steps and a novel, custom modified tray to successfully fabricate CAD-CAM milled CDs. The second technique highlights a nearly digital workflow for manufacturing a CAD-CAM milled CD and a milled resin interim removable partial denture.