en
Scientific article
English

Why the TimeToStop trial failed to recruit: a survey on antiepileptic drug withdrawal after paediatric epilepsy surgery

Published inEpileptic Disorders, vol. 20, no. 5, p. 374-385
Publication date2018
Abstract

Following the results of the multicentre European retrospective "TimeToStop" cohort study, we initiated a randomised trial to determine cognitive benefits of early postoperative antiepileptic drug withdrawal. Unfortunately, the trial failed to recruit and was terminated, as almost all parents preferred early drug withdrawal. The objectives of the current survey were to obtain insight into current practices regarding drug withdrawal after paediatric epilepsy surgery among epileptologists, and better understand the reasons for difficulties in recruitment.

Keywords
  • Anticonvulsive medication
  • Children
  • Discontinuation
  • Epilepsy surgery
  • Epileptologist
Citation (ISO format)
LAMBERINK, Herm J et al. Why the TimeToStop trial failed to recruit: a survey on antiepileptic drug withdrawal after paediatric epilepsy surgery. In: Epileptic Disorders, 2018, vol. 20, n° 5, p. 374–385. doi: 10.1684/epd.2018.1003
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1294-9361
251views
0downloads

Technical informations

Creation09/30/2019 9:33:00 AM
First validation09/30/2019 9:33:00 AM
Update time03/15/2023 6:05:46 PM
Status update03/15/2023 6:05:46 PM
Last indexation01/17/2024 6:23:05 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack