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Synchronous unicentric castleman disease and inflammatory hepatocellular adenoma: a case report

Authors
Papathomas G, Thomas
Pedica, Federica
Kane, Pauline
Amir, Ali
Heaton, Nigel
Quaglia, Alberto
Published in Annals of Hepatology. 2019, vol. 18, no. 1, p. 263-268
Abstract Systemic symptoms such as fever and fatigue are non-specific manifestations spanning from inflammation to neoplasia. Here we report the case of a 34 year-old man who presented with systemic symptoms for four months. CT-scan and MRI revealed a 3.4 cm arterialized hepatic lesion and a 7 cm paraduodenal mass. Surgical resection of both lesions and histological examination revealed an inflammatory hepatocellular adenoma and a unicentric plasma cell type of Castleman disease. Moreover, a diffuse AA amyloid deposition in the liver was observed. Resection of both lesions was associated with an improvement of the symptoms. To our knowledge, this is the first report of a synchronous presentation of a unicentric plasma cell type of Castleman disease, inflammatory hepatocellular adenoma and AA amyloidosis.
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PMID: 31113603
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DE VITO, Claudio et al. Synchronous unicentric castleman disease and inflammatory hepatocellular adenoma: a case report. In: Annals of Hepatology, 2019, vol. 18, n° 1, p. 263-268. doi: 10.5604/01.3001.0012.7936 https://archive-ouverte.unige.ch/unige:122470

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Deposited on : 2019-09-02

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