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Title

Antibodies against the C-terminus of apoA-1 are inversely associated with cholesterol efflux capacity and HDL metabolism in subjects with and without type 2 diabetes mellitus

Authors
Dullaart, Robin P F
Perton, Frank G
Published in International Journal of Molecular Sciences. 2019, vol. 20, no. 3, p. E732
Abstract We determined relationships of cholesterol efflux capacity (CEC), plasma cholesterol esterification (EST) and cholesteryl ester transfer (CET) with anti-c-terminus apoA-1 (Ac-terAA1) and anti-apolipoprotein (apo)-1 (AAA1) autoantibodies in subjects with and without Type 2 diabetes mellitus (T2D).
Keywords AntibodiesMonoclonal/pharmacologyApolipoprotein A-I/antagonists & inhibitors/chemistryBiological TransportBiomarkersCase-Control StudiesCholesterol/metabolismCholesterolHDL/metabolismDiabetes MellitusType 2/metabolismFemaleHumansLipid Metabolism/drug effectsMaleProtein Interaction Domains and Motifs/drug effects
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PMID: 30744100
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Article (Published version) (289 Kb) - public document Free access
Structures
Research group Chimie et protéomique clinique (270)
Project FNS: 310030-163335
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(ISO format)
DULLAART, Robin P F et al. Antibodies against the C-terminus of apoA-1 are inversely associated with cholesterol efflux capacity and HDL metabolism in subjects with and without type 2 diabetes mellitus. In: International Journal of Molecular Sciences, 2019, vol. 20, n° 3, p. E732. doi: 10.3390/ijms20030732 https://archive-ouverte.unige.ch/unige:121603

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Deposited on : 2019-08-15

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