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Scientific Article
unige:12151 
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Strand separation in negatively supercoiled dna |
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| Author | ||
| Published in | Journal of Mathematical Biology. 2005, vol. 51, no. 2, p. 198-216 | |
| Abstract | We consider Benham's model for strand separation in negatively supercoiled circular DNA, and study denaturation as function of the superhelical density k < 0. We propose a statistical version of this model, based on bayesian segmentation methods of current use in bioinformatics; this leads to new algorithms with priors adapted to supercoiled DNA, taking into account the random nature of the free energies needed to denature hydrogen bonds. | |
| Identifiers | arXiv: cond-mat/0306476v1 | |
| Note | 20 pages | |
| Full text | ||
| Structures | ||
| Citation (ISO format) | MAZZA, Christian. Strand separation in negatively supercoiled dna. In: Journal of Mathematical Biology, 2005, vol. 51, n° 2, p. 198-216. doi: 10.1007/s00285-005-0320-z https://archive-ouverte.unige.ch/unige:12151 |
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