Enantioselective 1,6-Conjugate Addition to Cyclic Dienones Catalyzed by the Cu−DiPPAM Complex

Wencel-Delord, Joanna; Alexakis, Alexandre; Crévisy, Christophe; Mauduit, Marc

doi:10.1021/ol1017382

Scientific article

English

Enantioselective 1,6-Conjugate Addition to Cyclic Dienones Catalyzed by the Cu−DiPPAM Complex

ContributorsWencel-Delord, Joanna; Alexakis, Alexandre; Crévisy, Christophe; Mauduit, Marc

Published inOrganic letters, vol. 12, no. 19, p. 4335-4337

Publication date2010

Abstract

In the presence of a Cu/DiPPAM catalytic system, various diorganozinc reagents realize 1,6-asymmetric conjugate addition on various cyclic five- and six-membered cyclic dienones, with complete regioselectivity and high ee's (93−99%).

Affiliation

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

WENCEL-DELORD, Joanna et al. Enantioselective 1,6-Conjugate Addition to Cyclic Dienones Catalyzed by the Cu−DiPPAM Complex. In: Organic letters, 2010, vol. 12, n° 19, p. 4335–4337. doi: 10.1021/ol1017382

Article (Published version)

Identifiers

PID : unige:12130
DOI : 10.1021/ol1017382

ISSN of the journal1523-7052

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Enantioselective 1,6-Conjugate Addition to Cyclic Dienones Catalyzed by the Cu−DiPPAM Complex

In the presence of a Cu/DiPPAM catalytic system, various diorganozinc reagents realize 1,6-asymmetric conjugate addition on various cyclic five- and six-membered cyclic dienones, with complete regioselectivity and high ee's (93−99%).

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