Medical imaging plays an important role in care of patients with musculoskeletal pathologies. In this field, all Imaging modalities are useful, providing morphological and functional information. The presence of metallic implants and the complexity of structures require an update of imaging techniques to better understand the structural static data. Finally, imaging- guided treatment of bone and soft tissue diseases has benefited from the developing techniques to achieve an optimal target with minor adverse effects. This thesis describes the evolution in this direction in selected fields of musculoskeletal imaging.