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Scientific article
English

Quality of life and social integration after allogeneic hematopoietic SCT

Contributors

Bieri, Stefan; Roosnek, Eddy Emile; Helg, C.; Verholen, F.; Robert, D.; Chapuis, B.; Passweg, Jakob; Miralbell, Raymond; Chalandon, Yves

Published in

Bone marrow transplantation, vol. 42, no. 12, p. 819-827

Publication date

2008

Abstract

In total, 124 adult patients in remission after allogeneic hematopoietic SCT (HSCT) participated in a cross-sectional study to assess health-related quality of life (HRQL). Assessment of HRQL was carried out using two questionnaires: the (EORTC QLQ-C30) and the Functional Assessment of Cancer Therapy (FACT) with specific modules for BMT (FACT-BMT). Transplanted patients differed from healthy controls in many HRQL-related dimensions in the EORTC QLQ-C30: social functioning 73.4 versus 85.8, P<0.0001; role functioning 74.6 versus 83.3, P<0.004; physical functioning 83.9 versus 89.9, P<0.001; emotional functioning 72.2 versus 82.8, P<0.0001 but were not significant for global HRQL 71.2 versus 75.3, P<0.03. In total, 60% of the patients returned to work after HSCT; 31% part time and 29% full time. Age at HSCT and employment status were significantly associated with HRQL. Other factors such as disease and disease stage and especially the occurrence of late complications did not impact the perception of HRQL. This study suggests that the perception of HRQL after HSCT differs from the general population. Issues to increase work-related capabilities and improve social support need to be addressed.

Keywords

  • Adult
  • Age Factors
  • Aged
  • Cross-Sectional Studies
  • Employment
  • Female
  • Hematopoietic Stem Cell Transplantation
  • Humans
  • Male
  • Middle Aged
  • Quality of Life
  • Social Adjustment
  • Social Support
  • Survivors
  • Transplantation, Homologous
  • Young Adult

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

BIERI, Stefan et al. Quality of life and social integration after allogeneic hematopoietic SCT. In: Bone marrow transplantation, 2008, vol. 42, n° 12, p. 819–827. doi: 10.1038/bmt.2008.253

Main files (1)

Article (Accepted version)

Identifiers

Additional URL for this publication

http://www.nature.com/bmt/journal/v42/n12/full/bmt2008253a.html

Journal ISSN

0268-3369
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Technical informations

Creation

19/03/2009 17:11:00

First validation

19/03/2009 17:11:00

Update

14/03/2023 15:03:34

Status update

14/03/2023 15:03:34

Last indexation

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