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Scientific article
English

Biatrial anatomical reverse remodelling after radiofrequency catheter ablation for atrial fibrillation: evidence from real-time three-dimensional echocardiography

Contributors

Mueller, Hajo; Noble, Stéphane Laurent; Keller, Pierre-Frédéric; Sigaud, Philippe; Gentil, Pascale; Lerch, René; Shah, Dipen; Burri, Haran

Published in

Europace, vol. 10, no. 9, p. 1073-1078

Publication date

2008

Abstract

AIMS: Reports using two-dimensional echocardiography have indicated that radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) results in a reduction in the left atrial (LA) size. Furthermore, the effect of pulmonary vein isolation (PVI) on right atrial (RA) anatomical remodelling has not been studied. Three-dimensional echocardiography (3DE) allows us to more precisely quantify atrial volume. Our aim was to assess the effect of PVI on biatrial anatomical remodelling using real-time 3DE. METHODS AND RESULTS: We prospectively studied 91 patients (age 59 +/- 8 years, 79 males) referred for RFCA of paroxysmal (n = 79) or chronic (n = 19) AF. Left atrial and RA volumes were measured using real-time 3DE at baseline and after 6 months of follow-up. Data on AF recurrences were also collected. Left atrial volume was significantly reduced at follow-up when compared with baseline (51 +/- 16 vs. 60 +/- 21 mL, P < 0.001). The same occurred with RA volume (43 +/- 17 vs. 50 +/- 20 mL, P = 0.001). The reduction in the LA volume was more marked in patients with chronic than in those with paroxysmal AF (17 +/- 16 vs. 6 +/- 17 mL, P = 0.017). Patients with AF recurrence (23%) showed similar atrial volume reduction compared with those who were seemingly cured. CONCLUSION: Three-dimensional echocardiography shows evidence of biatrial anatomical reverse remodelling after RFCA for AF. A reduction in the atrial volume occurs despite recurrence of AF.

Keywords

  • Atrial Fibrillation/surgery/ultrasonography
  • Catheter Ablation/methods
  • Computer Systems
  • Echocardiography, Three-Dimensional/methods
  • Female
  • Heart Atria/surgery/ultrasonography
  • Humans
  • Male
  • Middle Aged
  • Treatment Outcome
  • Ventricular Remodeling

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

MUELLER, Hajo et al. Biatrial anatomical reverse remodelling after radiofrequency catheter ablation for atrial fibrillation: evidence from real-time three-dimensional echocardiography. In: Europace, 2008, vol. 10, n° 9, p. 1073–1078. doi: 10.1093/europace/eun187

Main files (1)

Article (Accepted version)

Identifiers

Additional URL for this publication

http://europace.oxfordjournals.org/cgi/content/full/10/9/1073

Journal ISSN

1099-5129
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Technical informations

Creation

19/03/2009 14:32:00

First validation

19/03/2009 14:32:00

Update

26/03/2026 10:43:27

Status update

26/03/2026 10:43:27

Last indexation

26/03/2026 10:48:46
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