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Scientific article
English

A new potent antifungal 'quinone methide' diterpene with a cassane skeleton from Bobgunnia madagascariensis

Published inHelvetica chimica acta, vol. 83, p. 407-413
Publication date2000
Abstract

A new 'quinone methide' diterpene with a cassane skeleton was isolated from the root bark of Bobgunnia madagascariensis (DESV.) J.H. KIRKBR. et WIERSEMA (Leguminosae). Its structure was established as (4bS,8aS)-4b,5,6,7,8,8a-hexahydro-4-hydroxy-2-(2-hydroxyethyl)-1,4b,8,8-tetramethylphenathrene-3,9-dione by spectroscopic methods including single-crystal X-ray analysis. This compound showed strong antifungal properties towards human pathogenic fungi, in particular the yeast Candida albicans.

Keywords
  • Bobgunnia madagascariensis (DESV
  • Single-crystal X-ray analysis
  • Antifungal properties
Affiliation Not a UNIGE publication
Citation (ISO format)
SCHALLER, F. et al. A new potent antifungal “quinone methide” diterpene with a cassane skeleton from Bobgunnia madagascariensis. In: Helvetica chimica acta, 2000, vol. 83, p. 407–413.
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
  • PID : unige:11780
ISSN of the journal0018-019X
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