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Scientific article
English

An LC/DAD-UV/MS method for the rapid detection of aristolochic acid in plant preparations

Published inPlanta medica, vol. 68, p. 856-858
Publication date2002
Abstract

A new method using direct on-line coupling between HPLC and UV-DAD/MS was developed for the rapid detection of aristolochic acid 1 in plant preparations. The use of both UV-DAD and MS detectors enables this method to be very selective. A ng range detection limit was determined for both UV and MS detections. A quantitative determination of aristolochic acid 1 in plant preparations was achieved using UV and MS detection. A thin layer chromatography assay was also developed for the preliminary detection of aristolochic acid 1 in complex mixtures.

Keywords
  • chinese herbs nephropathy
  • renal-failure
  • identification
Affiliation Not a UNIGE publication
Citation (ISO format)
IOSET, Jean-Robert, RAOELISON, G.E., HOSTETTMANN, Kurt. An LC/DAD-UV/MS method for the rapid detection of aristolochic acid in plant preparations. In: Planta medica, 2002, vol. 68, p. 856–858. doi: 10.1055/s-2002-34413
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Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0032-0943
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