Cell-based bioreporter assay coupled to HPLC micro-fractionation in the evaluation of antimicrobial properties of the basidiomycete fungus Pycnoporus cinnabarinus

Järvinen, Päivi; Nybond, Susanna; Marcourt, Laurence; Ferreira Queiroz, Emerson; Wolfender, Jean-Luc; Mettälä, Aila; Karp, Matti; Vuorela, Heikki; Vuorela, Pia; Hatakka, Annele; Tammela, Päivi

doi:10.3109/13880209.2015.1103754

Scientific article

English

Cell-based bioreporter assay coupled to HPLC micro-fractionation in the evaluation of antimicrobial properties of the basidiomycete fungus Pycnoporus cinnabarinus

ContributorsJärvinen, Päivi; Nybond, Susanna; Marcourt, Laurence; Ferreira Queiroz, Emerson; Wolfender, Jean-Luc; Mettälä, Aila; Karp, Matti; Vuorela, Heikki; Vuorela, Pia; Hatakka, Annele; Tammela, Päivi

Published inPharmaceutical Biology, vol. 54, no. 6, p. 1108-1115

Publication date2016

Abstract

Identification of bioactive components from complex natural product extracts can be a tedious process that aggravates the use of natural products in drug discovery campaigns.

Keywords

Anti-Infective Agents/isolation & purification/pharmacology
Chemical Fractionation/methods
Chromatography
High Pressure Liquid/methods
Chromatography
Thin Layer
Complex Mixtures/isolation & purification/pharmacology
Escherichia coli K12/drug effects/growth & development
Liquid Phase Microextraction
Microbial Sensitivity Tests
Pycnoporus/chemistry/growth & development

Affiliation entities

Faculté des sciences / Section des sciences pharmaceutiques

Research groups

Phytochimie et produits naturels bioactifs

Citation (ISO format)

JÄRVINEN, Päivi et al. Cell-based bioreporter assay coupled to HPLC micro-fractionation in the evaluation of antimicrobial properties of the basidiomycete fungus Pycnoporus cinnabarinus. In: Pharmaceutical Biology, 2016, vol. 54, n° 6, p. 1108–1115. doi: 10.3109/13880209.2015.1103754

Article (Published version)

Identifiers

PID : unige:116645
DOI : 10.3109/13880209.2015.1103754
PMID : 26808592

Journal ISSN1388-0209

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Cell-based bioreporter assay coupled to HPLC micro-fractionation in the evaluation of antimicrobial properties of the basidiomycete fungus Pycnoporus cinnabarinus

Identification of bioactive components from complex natural product extracts can be a tedious process that aggravates the use of natural products in drug discovery campaigns.

Technical informations