Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

doi:10.1016/j.jalz.2018.02.009

Scientific article

English

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

CollaboratorsFrisoni, Giovanni; Popp, Julius

Published inAlzheimer's & Dementia, vol. 14, no. 7, p. 913-924

Publication date2018

Abstract

Apolipoprotein E (APOE) ε4 is the major genetic risk factor for Alzheimer's disease (AD), but its prevalence is unclear because earlier studies did not require biomarker evidence of amyloid β (Aβ) pathology.

Keywords

APOE
Age
Alzheimer's disease
Amyloid
CSF
Education
Geographical location
Mild cognitive impairment
PET
Prevalence
Sex
Subjective cognitive decline

Affiliation entities

Research groups

Citation (ISO format)

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer’s disease. In: Alzheimer’s & Dementia, 2018, vol. 14, n° 7, p. 913–924. doi: 10.1016/j.jalz.2018.02.009

Article (Published version)

Identifiers

PID : unige:116120
DOI : 10.1016/j.jalz.2018.02.009
PMID : 29601787

Journal ISSN1552-5260

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Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

Apolipoprotein E (APOE) ε4 is the major genetic risk factor for Alzheimer's disease (AD), but its prevalence is unclear because earlier studies did not require biomarker evidence of amyloid β (Aβ) pathology.

Technical informations