Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study

Genetic Frontotemporal dementia Initiative (GENFI)

doi:10.1002/acn3.601

Scientific article

English

Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study

ContributorsGenetic Frontotemporal dementia Initiative (GENFI)

CollaboratorsFrisoni, Giovanni

Published inAnnals of Clinical and Translational Neurology, vol. 5, no. 9, p. 1025-1036

Publication date2018

Abstract

We aimed to investigate mutation-specific white matter (WM) integrity changes in presymptomatic and symptomatic mutation carriers of the C9orf72,MAPT, and GRN mutations by use of diffusion-weighted imaging within the Genetic Frontotemporal dementia Initiative (GENFI) study.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie

Research groups

Troubles de mémoire et maladie d'Alzeimer (935)

Citation (ISO format)

Genetic Frontotemporal dementia Initiative (GENFI). Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study. In: Annals of Clinical and Translational Neurology, 2018, vol. 5, n° 9, p. 1025–1036. doi: 10.1002/acn3.601

Article (Published version)

CC BY

Identifiers

PID : unige:116098
DOI : 10.1002/acn3.601
PMID : 30250860

Journal ISSN2328-9503

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183downloads

Creation10/04/2019 14:17:00

First validation10/04/2019 14:17:00

Update15/03/2023 16:20:57

Status update15/03/2023 16:20:56

Last indexation31/10/2024 13:13:14

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Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study

We aimed to investigate mutation-specific white matter (WM) integrity changes in presymptomatic and symptomatic mutation carriers of the C9orf72,MAPT, and GRN mutations by use of diffusion-weighted imaging within the Genetic Frontotemporal dementia Initiative (GENFI) study.

Technical informations