Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort

Sellami, Leila; Bocchetta, Martina; Masellis, Mario; Cash, David M; Dick, Katrina M; van Swieten, John; Borroni, Barbara; Galimberti, Daniela; Tartaglia, Maria Carmela; Rowe, James B; Graff, Caroline; Tagliavini, Fabrizio; Frisoni, Giovanni; Finger, Elizabeth; de Mendonça, Alexandre; Sorbi, Sandro; Warren, Jason D; Rohrer, Jonathan D; Laforce, Robert

doi:10.3233/JAD-180053

Scientific article

English

Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort

ContributorsSellami, Leila; Bocchetta, Martina; Masellis, Mario; Cash, David M; Dick, Katrina M; van Swieten, John; Borroni, Barbara; Galimberti, Daniela; Tartaglia, Maria Carmela; Rowe, James B; Graff, Caroline; Tagliavini, Fabrizio; Frisoni, Giovanni; Finger, Elizabeth; de Mendonça, Alexandre; Sorbi, Sandro; Warren, Jason D; Rohrer, Jonathan D; Laforce, Robert

Published inJournal of Alzheimer's Disease, vol. 65, no. 1, p. 147-163

Publication date2018

Abstract

The overlap between frontotemporal dementia (FTD) and primary psychiatric disorders has been brought to light by reports of prominent neuropsychiatric symptoms (NPS) in FTD-related genetic mutations, particularly among C9orf72 and GRN carriers. It has been recently demonstrated that early neuroanatomical changes in genetic FTD may be different across the major disease-causing mutations.

Keywords

Frontotemporal dementia
genetics
magnetic resonance imaging
neuropsychiatry

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie

Research groups

Troubles de mémoire et maladie d'Alzeimer (935)

Citation (ISO format)

SELLAMI, Leila et al. Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort. In: Journal of Alzheimer’s Disease, 2018, vol. 65, n° 1, p. 147–163. doi: 10.3233/JAD-180053

Article (Published version)

Identifiers

PID : unige:116066
DOI : 10.3233/JAD-180053
PMID : 30010122

Journal ISSN1387-2877

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Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort

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