Association of Second Allogeneic Hematopoietic Cell Transplant vs Donor Lymphocyte Infusion With Overall Survival in Patients With Acute Myeloid Leukemia Relapse

Kharfan-Dabaja, Mohamed A; Labopin, Myriam; Polge, Emmanuelle; Nishihori, Taiga; Bazarbachi, Ali; Finke, Jürgen; Stadler, Michael; Ehninger, Gerhard; Lioure, Bruno; Schaap, Nicolaas; Afanasyev, Boris; Yeshurun, Moshe; Isaksson, Cecilia; Maertens, Johan; Chalandon, Yves; Schmid, Christoph; Nagler, Arnon; Mohty, Mohamad

doi:10.1001/jamaoncol.2018.2091

Scientific article

English

Association of Second Allogeneic Hematopoietic Cell Transplant vs Donor Lymphocyte Infusion With Overall Survival in Patients With Acute Myeloid Leukemia Relapse

ContributorsKharfan-Dabaja, Mohamed A; Labopin, Myriam; Polge, Emmanuelle; Nishihori, Taiga; Bazarbachi, Ali; Finke, Jürgen; Stadler, Michael; Ehninger, Gerhard; Lioure, Bruno; Schaap, Nicolaas; Afanasyev, Boris; Yeshurun, Moshe; Isaksson, Cecilia; Maertens, Johan; Chalandon, Yves; Schmid, Christoph; Nagler, Arnon; Mohty, Mohamad

Published inJAMA Oncology, vol. 4, no. 9, p. 1245-1253

Publication date2018

Abstract

The optimal treatment approach to patients with acute myeloid leukemia (AML) who relapse after an allogeneic hematopoietic cell transplant (allo-HCT) remains elusive. No randomized clinical trial comparing survival outcomes of a second allo-HCT (allo-HCT2) vs donor lymphocyte infusion (DLI) has been conducted to date.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Leucémie et transplantation allogénique de cellules souches hématopoïétiques (982)

Citation (ISO format)

KHARFAN-DABAJA, Mohamed A et al. Association of Second Allogeneic Hematopoietic Cell Transplant vs Donor Lymphocyte Infusion With Overall Survival in Patients With Acute Myeloid Leukemia Relapse. In: JAMA Oncology, 2018, vol. 4, n° 9, p. 1245–1253. doi: 10.1001/jamaoncol.2018.2091

Article (Published version)

Identifiers

PID : unige:115515
DOI : 10.1001/jamaoncol.2018.2091
PMID : 30003233

Journal ISSN2374-2437

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Association of Second Allogeneic Hematopoietic Cell Transplant vs Donor Lymphocyte Infusion With Overall Survival in Patients With Acute Myeloid Leukemia Relapse

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