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Title

The diagram: An analytical interpretation of oxygen transport in arterial blood during exercise in humans

Authors
Fagoni, Nazzareno
Published in Respiratory Physiology & Neurobiology. 2014, vol. 193, p. 55-61
Abstract A new analysis of the relationship between cardiac output (Q˙) and oxygen consumption V˙O2 is presented (Q˙-V˙O2 diagram). Data from different sources in the literature have been used for validation in three conditions: exercise and rest in normoxia, and exercise in hypoxia. The effects of changes in arterial oxygen concentration CaO2 on Q˙ are discussed, as well as the effects of predominant sympathetic or vagal stimulation. Differences appear depending on whether CaO2 is varied by means of changes in blood haemoglobin concentration or changes in arterial oxygen saturation. The present Q˙-V˙O2 diagram allows comprehensive description of oxygen transport in exercising humans; it expands applicability of the historical Q˙-V˙O2 relationship to include CaO2 variations; it opens new pathways for understanding underlying mechanisms; it allows computation of Q˙ from CaO2 and V˙O2 measurements, when Q˙ cannot be measured.
Keywords Arterial oxygen concentrationCardiac outputHypoxiaOxygen uptake
Identifiers
PMID: 24440436
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Structures
Research group Métabolisme énergétique (642)
Project FNS: 32003B_127620
Citation
(ISO format)
ADAMI, Alessandra, FAGONI, Nazzareno, FERRETTI, Guido. The diagram: An analytical interpretation of oxygen transport in arterial blood during exercise in humans. In: Respiratory Physiology & Neurobiology, 2014, vol. 193, p. 55-61. https://archive-ouverte.unige.ch/unige:115348

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Deposited on : 2019-03-25

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