Cardiovascular responses to dry apnoeas at exercise in air and in pure oxygen

Taboni, Anna; Vinetti, Giovanni; Bruseghini, Paolo; Camelio, Stefano; D'Elia, Matteo; Moia, Christian; Ferretti, Guido; Fagoni, Nazzareno

doi:10.1016/j.resp.2018.05.003

Scientific article

English

Cardiovascular responses to dry apnoeas at exercise in air and in pure oxygen

Contributors

Taboni, Anna; Vinetti, Giovanni; Bruseghini, Paolo; Camelio, Stefano; D'Elia, Matteo; Moia, Christian; Ferretti, Guido; Fagoni, Nazzareno

Published in

Respiratory Physiology & Neurobiology, vol. 255, p. 17-21

Publication date

2018

Abstract

If, as postulated, the end of the steady state phase (φ2) of cardiovascular responses to apnoea corresponds to the physiological breaking point, then we may hypothesize that φ2 should become visible if exercise apnoeas are performed in pure oxygen. We tested this hypothesis on 9 professional divers by means of continuous recording of blood pressure (BP), heart rate (fH), stroke volume (QS), and arterial oxygen saturation (SpO2) during dry maximal exercising apnoeas in ambient air and in oxygen. Apnoeas lasted 45.0 ± 16.9 s in air and 77.0 ± 28.9 s in oxygen (p < 0.05). In air, no φ2 was observed. Conversely, in oxygen, a φ2 of 28 ± 5 s duration appeared, during which systolic BP (185 ± 29 mmHg), fH (93 ± 16 bpm) and QS (91 ± 16 ml) remained stable. End-apnoea SpO2 was 95.5 ± 1.9% in air and 100% in oxygen. The results support the tested hypothesis.

Keywords

Blood pressure
Breath-hold
Heart rate
Physiological breaking point

UNIGE affiliation entities

Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences

UNIGE research groups

Métabolisme énergétique (642)

Funding

Swiss National Science Foundation - Dynamics of pulmonary gas exchange and systemic oxygen delivery during exercise transients in patients affected by specific cardiopulmonary diseases [127620]
Swiss National Science Foundation - 3200B0_114033

Citation (ISO format)

TABONI, Anna et al. Cardiovascular responses to dry apnoeas at exercise in air and in pure oxygen. In: Respiratory Physiology & Neurobiology, 2018, vol. 255, p. 17–21. doi: 10.1016/j.resp.2018.05.003

Article (Published version)

Identifiers

PID : unige:115347
DOI : 10.1016/j.resp.2018.05.003
PMID : 29733980

Additional URL for this publication

https://linkinghub.elsevier.com/retrieve/pii/S1569904818300739

Journal ISSN

1569-9048

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3downloads

Creation

12/11/2018 10:12:00

First validation

12/11/2018 10:12:00

Update

20/01/2025 09:15:41

Status update

20/01/2025 09:15:41

Last indexation

20/01/2025 09:24:03

Cardiovascular responses to dry apnoeas at exercise in air and in pure oxygen

Contributors

Published in

Publication date

Abstract

Keywords

UNIGE affiliation entities

UNIGE research groups

Funding

Citation (ISO format)

Main files (1)

Identifiers

Additional URL for this publication

Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation