Dereplication of plant phenolics using a mass-spectrometry database independent method

Borges, Ricardo M; Taujale, Rahil; de Souza, Juliana Santana; de Andrade Bezerra, Thaís; Silva, Eder Lana E; Herzog, Ronny; Ponce, Francesca V; Wolfender, Jean-Luc; Edison, Arthur S

doi:10.1002/pca.2773

Scientific article

English

Dereplication of plant phenolics using a mass-spectrometry database independent method

ContributorsBorges, Ricardo M; Taujale, Rahil; de Souza, Juliana Santana; de Andrade Bezerra, Thaís; Silva, Eder Lana E; Herzog, Ronny; Ponce, Francesca V; Wolfender, Jean-Luc; Edison, Arthur S

Published inPhytochemical Analysis, vol. 29, no. 6, p. 601-612

Publication date2018

Abstract

Dereplication, an approach to sidestep the efforts involved in the isolation of known compounds, is generally accepted as being the first stage of novel discoveries in natural product research. It is based on metabolite profiling analysis of complex natural extracts.

Keywords

Animals
Biological Products/chemistry
Caenorhabditis elegans
Databases, Factual
Lipid Metabolism
Metabolomics
Molecular Structure
Phenols/chemistry/metabolism
Plant Extracts/chemistry
Software
Tandem Mass Spectrometry/methods

Affiliation entities

Faculté des sciences / Section des sciences pharmaceutiques

Research groups

Phytochimie et produits naturels bioactifs

Citation (ISO format)

BORGES, Ricardo M et al. Dereplication of plant phenolics using a mass-spectrometry database independent method. In: Phytochemical Analysis, 2018, vol. 29, n° 6, p. 601–612. doi: 10.1002/pca.2773

Article (Published version)

Identifiers

PID : unige:114943
DOI : 10.1002/pca.2773
PMID : 29808582

Journal ISSN0958-0344

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Creation05/11/2018 10:50:00

First validation05/11/2018 10:50:00

Update15/03/2023 15:50:51

Status update15/03/2023 15:50:50

Last indexation31/10/2024 12:55:24

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Dereplication of plant phenolics using a mass-spectrometry database independent method

Dereplication, an approach to sidestep the efforts involved in the isolation of known compounds, is generally accepted as being the first stage of novel discoveries in natural product research. It is based on metabolite profiling analysis of complex natural extracts.

Technical informations