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2-Arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction

Publié dansCardiovascular Research, vol. 115, no. 3, p. 602-613
Date de publication2019
Résumé

Myocardial infarction (MI) leads to an enhanced release of endocannabinoids and a massive accumulation of neutrophils and monocytes within the ischaemic myocardium. These myeloid cells originate from haematopoietic precursors in the bone marrow and are rapidly mobilized in response to MI. We aimed to determine whether endocannabinoid signalling is involved in myeloid cell mobilization and cardiac recruitment after ischaemia onset.

Mots-clés
  • Myocardial infarction
  • Monocytes
  • Neutrophils
  • Monoacylglycerol lipase
  • CB2 cannabinoid receptor
Citation (format ISO)
SCHLOSS, Maximilian J et al. 2-Arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction. In: Cardiovascular Research, 2019, vol. 115, n° 3, p. 602–613. doi: 10.1093/cvr/cvy242
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Article (Accepted version)
accessLevelPublic
Identifiants
ISSN du journal0008-6363
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Informations techniques

Création25/02/2019 12:59:00
Première validation25/02/2019 12:59:00
Heure de mise à jour15/03/2023 15:48:38
Changement de statut15/03/2023 15:48:38
Dernière indexation17/01/2024 05:01:23
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