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Title

Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer's disease

Authors
Drzezga, Alexander
Festari, Cristina
Arbizu, Javier
Orini, Stefania
Herholz, Karl
Nestor, Peter
Agosta, Federica
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Published in European Journal of Nuclear Medicine and Molecular Imaging. 2018, vol. 45, no. 9, p. 1487-1496
Abstract To assess the clinical utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) for detection of early signs of neurodegeneration in conditions of increased risk for Alzheimer's disease (AD) as defined by: subjective cognitive decline (SCD), evidence of cerebral amyloid-pathology, apolipoprotein E (APOE) ε4-positive genotype, or autosomal dominant forms of AD (ADAD) in asymptomatic stages.
Keywords Alzheimer Disease/diagnostic imaging/geneticsApolipoproteins E/geneticsBrain/diagnostic imagingFluorodeoxyglucose F18Genetic Predisposition to DiseaseHumansPositron-Emission TomographyProspective StudiesRadiopharmaceuticals
Identifiers
PMID: 29756163
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Research group Troubles de mémoire et maladie d'Alzeimer (935)
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DRZEZGA, Alexander et al. Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer's disease. In: European Journal of Nuclear Medicine and Molecular Imaging, 2018, vol. 45, n° 9, p. 1487-1496. https://archive-ouverte.unige.ch/unige:114045

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Deposited on : 2019-02-08

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