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Scientific article
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Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer's disease

Published inEuropean Journal of Nuclear Medicine and Molecular Imaging, vol. 45, no. 9, p. 1487-1496
Publication date2018
Abstract

To assess the clinical utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) for detection of early signs of neurodegeneration in conditions of increased risk for Alzheimer's disease (AD) as defined by: subjective cognitive decline (SCD), evidence of cerebral amyloid-pathology, apolipoprotein E (APOE) ε4-positive genotype, or autosomal dominant forms of AD (ADAD) in asymptomatic stages.

Keywords
  • Alzheimer Disease/diagnostic imaging/genetics
  • Apolipoproteins E/genetics
  • Brain/diagnostic imaging
  • Fluorodeoxyglucose F18
  • Genetic Predisposition to Disease
  • Humans
  • Positron-Emission Tomography
  • Prospective Studies
  • Radiopharmaceuticals
Citation (ISO format)
DRZEZGA, Alexander et al. Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer’s disease. In: European Journal of Nuclear Medicine and Molecular Imaging, 2018, vol. 45, n° 9, p. 1487–1496. doi: 10.1007/s00259-018-4032-1
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Article (Published version)
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ISSN of the journal1619-7070
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