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Title

Nicotinic receptor abnormalities as a biomarker in idiopathic generalized epilepsy
Authors
Garibotto, Valentina
Wissmeyer, Michael
Giavri, Zoi
Goldstein, Rachel
Seimbille, Yann
Seeck, Margitta
Ratib, Osman
Haller, Sven
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Published in European journal of nuclear medicine and molecular imaging. 2019, vol. 46, no. 2, p. 385-395
Abstract Mutations of cholinergic neuronal nicotinic receptors have been identified in the autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE), associated with changes on PET images using [18F]-F-85380-A (F-A-85380), an α4β2 nicotinic receptor ligand. The aim of the present study was to evaluate potential changes in nicotinic receptor availability in other types of epilepsy.
Identifiers
PMID: 30269157
Full text
Article (Published version) (1 MB) - document accessible for UNIGE members only Limited access to UNIGE
Article (Accepted version) (1.1 MB) - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques
Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups Epilepsie et Chirurgie (149)
Imagerie per-opératoire multi-modalité en radiologie interventionnelle (949)
Laboratoire de neuroimagerie et de traceurs moléculaires innovants (984)
Project
Swiss National Science Foundation: 320030_127608
Citation
(ISO format) 		GARIBOTTO, Valentina et al. Nicotinic receptor abnormalities as a biomarker in idiopathic generalized epilepsy. In: European Journal of Nuclear Medicine and Molecular Imaging, 2019, vol. 46, n° 2, p. 385-395. doi: 10.1007/s00259-018-4175-0 https://archive-ouverte.unige.ch/unige:112562

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Deposited on : 2019-01-07

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