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Nicotinic receptor abnormalities as a biomarker in idiopathic generalized epilepsy

Published inEuropean Journal of Nuclear Medicine and Molecular Imaging, vol. 46, no. 2, p. 385-395
Publication date2019
Abstract

Mutations of cholinergic neuronal nicotinic receptors have been identified in the autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE), associated with changes on PET images using [18F]-F-85380-A (F-A-85380), an α4β2 nicotinic receptor ligand. The aim of the present study was to evaluate potential changes in nicotinic receptor availability in other types of epilepsy.

Citation (ISO format)
GARIBOTTO, Valentina et al. Nicotinic receptor abnormalities as a biomarker in idiopathic generalized epilepsy. In: European Journal of Nuclear Medicine and Molecular Imaging, 2019, vol. 46, n° 2, p. 385–395. doi: 10.1007/s00259-018-4175-0
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Journal ISSN1619-7070
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Creation11/15/2018 5:33:00 PM
First validation11/15/2018 5:33:00 PM
Update time01/20/2025 7:32:15 AM
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