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Title

Comparative efficacy and safety of second-line antiretroviral therapy for treatment of HIV/AIDS: a systematic review and network meta-analysis

Authors
Kanters, Steve
Socias, Maria Eugenia
Paton, Nicholas I
Vitoria, Marco
Doherty, Meg
Ayers, Dieter
Popoff, Evan
Chan, Keith
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Published in The Lancet HIV. 2017, vol. 4, no. 10, p. e433-e441
Abstract Selection of optimal second-line antiretroviral therapy (ART) has important clinical and programmatic implications. To inform the 2016 revision of the WHO ART guidelines, we assessed the comparative effectiveness and safety of available second-line ART regimens for adults and adolescents in whom first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens have failed.
Keywords Acquired Immunodeficiency Syndrome/drug therapyAdolescentAdultAnti-HIV Agents/administration & dosage/adverse effects/therapeutic useFemaleHIV Infections/drug therapyHIV Protease Inhibitors/administration & dosage/adverse effects/therapeutic useHIV-1/drug effectsHumansLopinavir/administration & dosage/adverse effects/therapeutic useMaleNetwork Meta-AnalysisProspective StudiesRaltegravir Potassium/administration & dosage/adverse effects/therapeutic useRetrospective StudiesReverse Transcriptase Inhibitors/administration & dosage/adverse effects/therapeutic useRitonavir/administration & dosage/adverse effects/therapeutic use
Identifiers
PMID: 28784426
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Research group VIH/SIDA (930)
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KANTERS, Steve et al. Comparative efficacy and safety of second-line antiretroviral therapy for treatment of HIV/AIDS: a systematic review and network meta-analysis. In: The Lancet HIV, 2017, vol. 4, n° 10, p. e433-e441. doi: 10.1016/S2352-3018(17)30109-1 https://archive-ouverte.unige.ch/unige:112379

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Deposited on : 2018-12-18

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