UNIGE document Scientific Article
previous document  unige:112109  next document
add to browser collection

Surgical interventions with fatal outcome: utility of multi-phase postmortem CT angiography

Zerlauth, J-B
Doenz, F
Uské, A
Meuli, R
Published in Forensic Science International. 2013, vol. 225, no. 1-3, p. 32-41
Abstract Cases of fatal outcome after surgical intervention are autopsied to determine the cause of death and to investigate whether medical error caused or contributed to the death. For medico-legal purposes, it is imperative that autopsy findings are documented clearly. Modern imaging techniques such as multi-detector computed tomography (MDCT) and postmortem CT angiography, which is used for vascular system imaging, are useful tools for determining cause of death. The aim of this study was to determine the utility of postmortem CT angiography for the medico-legal death investigation. This study investigated 10 medico-legal cases with a fatal outcome after surgical intervention using multi-phase postmortem whole body CT angiography. A native CT scan was performed as well as three angiographic phases (arterial, venous, and dynamic) using a Virtangio(®) perfusion device and the oily contrast agent, Angiofil(®). The results of conventional autopsy were compared to those from the radiological investigations. We also investigated whether the radiological findings affected the final interpretation of cause-of-death. Causes of death were hemorrhagic shock, intracerebral hemorrhage, septic shock, and a combination of hemorrhage and blood aspiration. The diagnoses were made by conventional autopsy as well as by postmortem CT angiography. Hemorrhage played an important role in eight of ten cases. The radiological exam revealed the exact source of bleeding in seven of the eight cases, whereas conventional autopsy localized the source of bleeding only generally in five of the seven cases. In one case, neither conventional autopsy nor CT angiography identified the source of hemorrhage. We conclude that postmortem CT angiography is extremely useful for investigating deaths following surgical interventions. This technique helps document autopsy findings and allows a second examination if it is needed; specifically, it detects and visualizes the sources of hemorrhages in detail, which is often of particular interest in such cases.
Keywords AdolescentAgedAngiography/methodsAutopsyCerebral Hemorrhage/pathologyContrast MediaExsanguination/pathologyFemaleForensic PathologyHumansIatrogenic DiseaseIntraoperative Complications/pathologyMaleMalpracticeMiddle AgedMultidetector Computed TomographyPostoperative Complications/pathologyRespiratory Aspiration/pathologyRetrospective StudiesShock, Hemorrhagic/pathologyShock, Septic/pathology
PMID: 22721937
Full text
Article (Published version) (1.2 MB) - document accessible for UNIGE members only Limited access to UNIGE
Research group Groupe Silke Grabherr (969)
(ISO format)
ZERLAUTH, J-B et al. Surgical interventions with fatal outcome: utility of multi-phase postmortem CT angiography. In: Forensic Science International, 2013, vol. 225, n° 1-3, p. 32-41. doi: 10.1016/j.forsciint.2012.05.013 https://archive-ouverte.unige.ch/unige:112109

231 hits

0 download


Deposited on : 2018-12-07

Export document
Format :
Citation style :