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Sudden coronary death in the young: Evidence of contractile phenotype of smooth muscle cells in the culprit atherosclerotic plaque

ContributorsRizzo, Stefania; Coen, Matteoorcid; Sakic, Antonija; De Gaspari, Monica; Thiene, Gaetano; Gabbiani, Giulio; Basso, Cristina; Piallat, Marie-Luce
Published inInternational Journal of Cardiology, vol. 264, p. 1-6
Publication date2018
Abstract

Culprit coronary atherosclerotic plaques (APs) from young sudden cardiac death (SCD) victims are mostly non-atheromatous, i.e., consisting of proliferative smooth muscle cells (SMCs). Coronary vasospasm has been advocated to explain plaque instability in the absence of thrombosis. Our aim was to characterize the SMC phenotype in the intima and media of coronary arteries from young SCD victims.

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RIZZO, Stefania et al. Sudden coronary death in the young: Evidence of contractile phenotype of smooth muscle cells in the culprit atherosclerotic plaque. In: International Journal of Cardiology, 2018, vol. 264, p. 1–6. doi: 10.1016/j.ijcard.2018.02.096
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ISSN of the journal0167-5273
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Creation11/29/2018 1:56:00 PM
First validation11/29/2018 1:56:00 PM
Update time03/15/2023 3:11:38 PM
Status update03/15/2023 3:11:37 PM
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