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Title

Sudden coronary death in the young: Evidence of contractile phenotype of smooth muscle cells in the culprit atherosclerotic plaque

Authors
Rizzo, Stefania
De Gaspari, Monica
Thiene, Gaetano
Basso, Cristina
Published in International Journal of Cardiology. 2018, vol. 264, p. 1-6
Abstract Culprit coronary atherosclerotic plaques (APs) from young sudden cardiac death (SCD) victims are mostly non-atheromatous, i.e., consisting of proliferative smooth muscle cells (SMCs). Coronary vasospasm has been advocated to explain plaque instability in the absence of thrombosis. Our aim was to characterize the SMC phenotype in the intima and media of coronary arteries from young SCD victims.
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PMID: 29776555
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Article (Published version) (2.1 MB) - document accessible for UNIGE members only Limited access to UNIGE
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Research group Bochaton-Piallat Marie-Luce (pathologie et immunologie) (646)
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RIZZO, Stefania et al. Sudden coronary death in the young: Evidence of contractile phenotype of smooth muscle cells in the culprit atherosclerotic plaque. In: International Journal of Cardiology, 2018, vol. 264, p. 1-6. doi: 10.1016/j.ijcard.2018.02.096 https://archive-ouverte.unige.ch/unige:112027

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Deposited on : 2018-12-05

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