Fusion genes with ALK as recurrent partner in ependymoma-like gliomas: a new brain tumor entity?

Olsen, Thale Kristin; Panagopoulos, Ioannis; Meling, Torstein; Micci, Francesca; Gorunova, Ludmila; Thorsen, Jim; Due-Tønnessen, Bernt; Scheie, David; Lund-Iversen, Marius; Krossnes, Bård; Saxhaug, Cathrine; Heim, Sverre; Brandal, Petter

doi:10.1093/neuonc/nov039

Scientific article

English

Fusion genes with ALK as recurrent partner in ependymoma-like gliomas: a new brain tumor entity?

ContributorsOlsen, Thale Kristin; Panagopoulos, Ioannis; Meling, Torstein; Micci, Francesca; Gorunova, Ludmila; Thorsen, Jim; Due-Tønnessen, Bernt; Scheie, David; Lund-Iversen, Marius; Krossnes, Bård; Saxhaug, Cathrine; Heim, Sverre; Brandal, Petter

Published inNeuro-Oncology, vol. 17, no. 10, p. 1365-1373

Publication date2015

Abstract

We have previously characterized 19 ependymal tumors using Giemsa banding and high-resolution comparative genomic hybridization. The aim of this study was to analyze these tumors searching for fusion genes.

Keywords

Adult
Aged
Brain Neoplasms/genetics/pathology
Chromosome Aberrations
Comparative Genomic Hybridization
Ependymoma/genetics/pathology
Female
Humans
Infant
Karyotyping
Male
Membrane Proteins/genetics
Microfilament Proteins/genetics
Middle Aged
Oncogene Proteins
Fusion/genetics
Receptor Protein-Tyrosine Kinases/genetics
Sequence Analysis
RNA
Vesicular Transport Proteins/genetics

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques

Research groups

Groupe Schaller Karl Lothard (neurochirurgie) (851)

Citation (ISO format)

OLSEN, Thale Kristin et al. Fusion genes with ALK as recurrent partner in ependymoma-like gliomas: a new brain tumor entity? In: Neuro-Oncology, 2015, vol. 17, n° 10, p. 1365–1373. doi: 10.1093/neuonc/nov039

Article (Published version)

OA OTHER

Identifiers

PID : unige:111893
DOI : 10.1093/neuonc/nov039
PMID : 25795305

Journal ISSN1522-8517

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Fusion genes with ALK as recurrent partner in ependymoma-like gliomas: a new brain tumor entity?

We have previously characterized 19 ependymal tumors using Giemsa banding and high-resolution comparative genomic hybridization. The aim of this study was to analyze these tumors searching for fusion genes.

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