UNIGE document Scientific Article
previous document  unige:111570  next document
add to browser collection
Title

Visualization of Myocardial Infarction in Postmortem Multiphase Computed Tomography Angiography: A Feasibility Study

Authors
Vanhaebost, Jessica
Doenz, Francesco
Michaud, Katarzyna
Published in American Journal of Forensic Medicine and Pathology. 2018, vol. 39, no. 2, p. 106-113
Abstract Recent studies have indicated that multiphase postmortem computed tomography angiography (MPMCTA) allows detection of a pathological enhancement of the myocardium in regions that correlate with the localization of the infarction at histology. The aim of this study was to verify this hypothesis by examining MPMCTA images in cases of myocardial infarction. Therefore, we investigated 10 autopsy cases where death was attributed to myocardial infarction or which showed cardiovascular pathology. As a control group, we selected 10 cases of non-natural (namely, not cardiac) death. The MPMCTA was performed in both groups to ascertain whether a pathological enhancement could be observed. We detected a myocardial enhancement in all cardiac death cases, in the same region that showed infarction at histology. No enhancement was observed in control cases. These results have important implications in the routine management of sudden cardiac death cases. In fact, MPMCTA can not only orient about the cause of death before autopsy, but can especially help to identify affected regions for guiding and improving the sampling for microscopic examination.
Keywords AdultAgedAged, 80 and overAutopsy/methodsCase-Control StudiesComputed Tomography AngiographyFeasibility StudiesFemaleHeart/diagnostic imagingHumansMaleMiddle AgedMyocardial Infarction/diagnostic imaging/pathologyMyocardium/pathology
Identifiers
PMID: 29438137
Full text
Article (Published version) (546 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Groupe Silke Grabherr (969)
Citation
(ISO format)
SABATASSO, Sara et al. Visualization of Myocardial Infarction in Postmortem Multiphase Computed Tomography Angiography: A Feasibility Study. In: American Journal of Forensic Medicine and Pathology, 2018, vol. 39, n° 2, p. 106-113. https://archive-ouverte.unige.ch/unige:111570

6 hits

0 download

Update

Deposited on : 2018-11-28

Export document
Format :
Citation style :