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Title

ONE SHOT - single shot radiotherapy for localized prostate cancer: study protocol of a single arm, multicenter phase I/II trial

Authors
Scorsetti, Marta
Franzese, Ciro
Förster, Robert
Giaj-Levra, Niccolò
Koustouvelis, Nikolaos
Bertaut, Aurelie
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Published in Radiation Oncology. 2018, vol. 13, no. 1, p. 166
Abstract Stereotactic body radiotherapy (SBRT) is an emerging treatment alternative for patients with localized prostate cancer. Promising results in terms of disease control and toxicity have been reported with 4 to 5 SBRT fractions. However, question of how far can the number of fractions with SBRT be reduced is a challenging research matter. As already explored by some authors in the context of brachytherapy, monotherapy appears to be feasible with an acceptable toxicity profile and a promising outcome. The aim of this multicenter phase I/II prospective trialis to demonstrate early evidence of safety and efficacy of a single-fraction SBRT approach for the treatment of localized disease.
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PMID: 30180867
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Article (Published version) (752 Kb) - public document Free access
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Research group Groupe Miralbell Raymond (radio-oncologie) (685)
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ZILLI, Thomas et al. ONE SHOT - single shot radiotherapy for localized prostate cancer: study protocol of a single arm, multicenter phase I/II trial. In: Radiation Oncology, 2018, vol. 13, n° 1, p. 166. https://archive-ouverte.unige.ch/unige:111080

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Deposited on : 2018-11-21

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