Impact of obesity on the response to tumor necrosis factor inhibitors in axial spondyloarthritis

Micheroli, Raphael; Hebeisen, Monika; Wildi, Lukas M; Exer, Pascale; Tamborrini, Giorgio; Bernhard, Jürg; Möller, Burkhard; Zufferey, Pascal; Nissen, Michaël; Scherer, Almut; Ciurea, Adrian

doi:10.1186/s13075-017-1372-3

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Title		Impact of obesity on the response to tumor necrosis factor inhibitors in axial spondyloarthritis
Authors		Micheroli, Raphael Hebeisen, Monika Wildi, Lukas M Exer, Pascale Tamborrini, Giorgio Bernhard, Jürg Möller, Burkhard Zufferey, Pascal Nissen, Michaël Scherer, Almut Ciurea, Adrian show all authors [1 - 11]
Published in		Arthritis Research and Therapy. 2017, vol. 19, no. 1, 164
Abstract		Few studies have investigated the impact of obesity on the response to tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA). The aim of our study was to investigate the impact of different body mass index (BMI) categories on TNFi response in a large cohort of patients with axSpA.
Keywords		Adult — Anti-Inflammatory Agents/therapeutic use — Cohort Studies — Female — Humans — Male — Obesity/complications — Spondylarthritis/drug therapy — Treatment Outcome — Tumor Necrosis Factor-alpha/antagonists & inhibitors
Identifiers		DOI: 10.1186/s13075-017-1372-3 PMID: 28724442
Full text		Article (Published version) (592 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine
Research groups		Mécanisme de l'inflammation articulaire (44) Recherche clinique en rhumatismes inflammatoires (1010)
Citation (ISO format)		MICHEROLI, Raphael et al. Impact of obesity on the response to tumor necrosis factor inhibitors in axial spondyloarthritis. In: Arthritis Research and Therapy, 2017, vol. 19, n° 1, p. 164. doi: 10.1186/s13075-017-1372-3 https://archive-ouverte.unige.ch/unige:110918