An alternative scheme for the multiplexed acquisition of 1D and 2D NMR spectra

Plainchont, Bertrand; Martinez, Agathe; Tisse, Severine; Bouillon, Jean-Philippe; Wieruszeski, Jean-Michel; Lippens, Guy; Jeannerat, Damien; Nuzillard, Jean-Marc

doi:10.1016/j.jmr.2010.06.005

Scientific article

English

An alternative scheme for the multiplexed acquisition of 1D and 2D NMR spectra

Contributors

Plainchont, Bertrand; Martinez, Agathe; Tisse, Severine; Bouillon, Jean-Philippe; Wieruszeski, Jean-Michel; Lippens, Guy; Jeannerat, Damien; Nuzillard, Jean-Marc

Published in

Journal of magnetic resonance, vol. 206, no. 1, p. 68-73

Publication date

2010

Abstract

Spin system selective 1D 1H, 2D DQF-COSY and 2D HSQC NMR spectra were recorded in order to fully assign the 1H and 13C 1D NMR spectra of an asymmetrical β-cyclodextrin derivative. Instead of individually accessing the seven sugar anomeric protons by means of long multiplet selective pulses, only short region selective pulses were used. The simultaneously selected anomeric protons were differentiated by allowing their magnetization to evolve under the sole effect of the chemical shift interaction. In each experiment, the seven recorded spectra were linear combinations of the seven desired ones. The combination coefficients were measured and used to obtain almost perfectly separated sugar unit sub-spectra. This multiplexed acquisition scheme resulted in a time gain factor of about 2.

Keywords

Multiplexed acquisition
Hadamard spectroscopy
Shaped pulses
TOCSY
COSY
HSQC
Cyclodextrin derivatives

UNIGE affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

PLAINCHONT, Bertrand et al. An alternative scheme for the multiplexed acquisition of 1D and 2D NMR spectra. In: Journal of magnetic resonance, 2010, vol. 206, n° 1, p. 68–73. doi: 10.1016/j.jmr.2010.06.005

Article (Published version)

Identifiers

PID : unige:11034
DOI : 10.1016/j.jmr.2010.06.005

Additional URL for this publication

http://linkinghub.elsevier.com/retrieve/pii/S1090780710001801

Journal ISSN

1090-7807

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Creation

24/08/2010 16:56:00

First validation

24/08/2010 16:56:00

Update

14/03/2023 16:02:01

Status update

14/03/2023 16:02:01

Last indexation

29/10/2024 16:48:19

An alternative scheme for the multiplexed acquisition of 1D and 2D NMR spectra

Contributors

Published in

Publication date

Abstract

Keywords

UNIGE affiliation entities

Citation (ISO format)

Main files (1)

Identifiers

Additional URL for this publication

Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation