Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study

Yang, Wan-Lin; Kouyos, Roger D; Scherrer, Alexandra U; Böni, Jürg; Shah, Cyril; Yerly Ferrillo, Sabine; Klimkait, Thomas; Aubert, Vincent; Hirzel, Cédric; Battegay, Manuel; Cavassini, Matthias; Bernasconi, Enos; Vernazza, Pietro; Held, Leonhard; Ledergerber, Bruno; Günthard, Huldrych F

doi:10.1093/jac/dkv257

Scientific article

English

Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study

ContributorsYang, Wan-Lin; Kouyos, Roger D; Scherrer, Alexandra U; Böni, Jürg; Shah, Cyril; Yerly Ferrillo, Sabine; Klimkait, Thomas; Aubert, Vincent; Hirzel, Cédric; Battegay, Manuel; Cavassini, Matthias; Bernasconi, Enos; Vernazza, Pietro; Held, Leonhard; Ledergerber, Bruno; Günthard, Huldrych F

Published inJournal of Antimicrobial Chemotherapy, vol. 70, no. 12, p. 3323-3331

Publication date2015

Abstract

The most recommended NRTI combinations as first-line antiretroviral treatment for HIV-1 infection in resource-rich settings are tenofovir/emtricitabine, abacavir/lamivudine, tenofovir/lamivudine and zidovudine/lamivudine. Efficacy studies of these combinations also considering pill numbers, dosing frequencies and ethnicities are rare.

Keywords

Adult
Antiretroviral Therapy
Highly Active/methods
Drug Resistance
Viral
Female
HIV Infections/drug therapy
HIV-1
Humans
Male
Middle Aged
Nucleosides/therapeutic use
Nucleotides/therapeutic use
Reverse Transcriptase Inhibitors/therapeutic use
Switzerland
Treatment Failure

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Virologie clinique (668)

Citation (ISO format)

YANG, Wan-Lin et al. Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study. In: Journal of Antimicrobial Chemotherapy, 2015, vol. 70, n° 12, p. 3323–3331. doi: 10.1093/jac/dkv257

Article (Published version)

CC0

Identifiers

PID : unige:110041
DOI : 10.1093/jac/dkv257
PMID : 26362944

Journal ISSN0305-7453

451views

216downloads

Creation04/09/2018 14:34:00

First validation04/09/2018 14:34:00

Update09/02/2026 15:32:38

Status update09/02/2026 15:32:38

Last indexation09/02/2026 15:37:08

Archive ouverte UNIGE

Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study

Technical informations