Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study

Yang, Wan-Lin; Kouyos, Roger D; Scherrer, Alexandra U; Böni, Jürg; Shah, Cyril; Yerly Ferrillo, Sabine; Klimkait, Thomas; Aubert, Vincent; Hirzel, Cédric; Battegay, Manuel; Cavassini, Matthias; Bernasconi, Enos; Vernazza, Pietro; Held, Leonhard; Ledergerber, Bruno; Günthard, Huldrych F

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Title		Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study
Authors		Yang, Wan-Lin Kouyos, Roger D Scherrer, Alexandra U Böni, Jürg Shah, Cyril Yerly Ferrillo, Sabine Klimkait, Thomas Aubert, Vincent Hirzel, Cédric Battegay, Manuel Cavassini, Matthias Bernasconi, Enos Vernazza, Pietro Held, Leonhard Ledergerber, Bruno Günthard, Huldrych F show all authors [1 - 16]
Published in		Journal of Antimicrobial Chemotherapy. 2015, vol. 70, no. 12, p. 3323-31
Abstract		The most recommended NRTI combinations as first-line antiretroviral treatment for HIV-1 infection in resource-rich settings are tenofovir/emtricitabine, abacavir/lamivudine, tenofovir/lamivudine and zidovudine/lamivudine. Efficacy studies of these combinations also considering pill numbers, dosing frequencies and ethnicities are rare.
Keywords		Adult — Antiretroviral Therapy — Highly Active/methods — Drug Resistance — Viral — Female — HIV Infections/drug therapy — HIV-1 — Humans — Male — Middle Aged — Nucleosides/therapeutic use — Nucleotides/therapeutic use — Reverse Transcriptase Inhibitors/therapeutic use — Switzerland — Treatment Failure
Identifiers		DOI: 10.1093/jac/dkv257 PMID: 26362944
Full text		Article (Published version) (326 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine interne des spécialités
Research group		Groupe Laurent Kaiser (virologie clinique) (668)
Citation (ISO format)		YANG, Wan-Lin et al. Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study. In: Journal of Antimicrobial Chemotherapy, 2015, vol. 70, n° 12, p. 3323-31. https://archive-ouverte.unige.ch/unige:110041