Article (Published version) (820 Kb) - Limited access to UNIGE
The Associations of Blood Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin with Progression from CKD to ESRD.
|Published in||Clinical Journal of the American Society of Nephrology. 2016, vol. 11, no. 12, p. 2141-2149|
|Abstract||Elevated levels of urinary kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin are associated with negative outcomes in CKD. Our study aimed to explore the prognostic accuracy of blood levels of kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin for progression to ESRD, major adverse cardiovascular events, and death in a large cohort of adult patients with all-cause nondialysis-dependent CKD stages 3-5. We considered whether these factors improve prediction in relation to traditional biomarkers and clinical parameters.|
|Keywords||Aged — Aged, 80 and over — Biomarkers/blood — Coronary Disease/surgery — Disease Progression — Female — Follow-Up Studies — Glomerular Filtration Rate — Hepatitis A Virus Cellular Receptor 1/blood — Humans — Kidney Failure, Chronic/blood/physiopathology/therapy — Lipocalin-2/blood — Male — Middle Aged — Mortality — Myocardial Infarction/blood — Prognosis — Proportional Hazards Models — Prospective Studies — ROC Curve — Renal Insufficiency, Chronic/blood — Risk Factors — Stroke/blood|
|Research group||Chimie et protéomique clinique (270)|
|ALDERSON, Helen V et al. The Associations of Blood Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin with Progression from CKD to ESRD. In: Clinical Journal of the American Society of Nephrology, 2016, vol. 11, n° 12, p. 2141-2149. doi: 10.2215/CJN.02670316 https://archive-ouverte.unige.ch/unige:108829|