Anti-apolipoprotein A-1 autoantibodies are associated with immunodeficiency and systemic inflammation in HIV patients

Satta Poschung, Nathalie; Pagano, Sabrina; Montecucco, Fabrizio; Gencer, Baris; Mach, François; Kaiser, Laurent; Calmy, Alexandra; Vuilleumier, Nicolas; Swiss HIV Cohort Study

doi:10.1016/j.jinf.2017.11.008

Scientific article

English

Anti-apolipoprotein A-1 autoantibodies are associated with immunodeficiency and systemic inflammation in HIV patients

ContributorsSatta Poschung, Nathalie; Pagano, Sabrina

; Montecucco, Fabrizio; Gencer, Baris; Mach, François; Kaiser, Laurent; Calmy, Alexandra

; Vuilleumier, Nicolas; Swiss HIV Cohort Study

Published inJournal of Infection, vol. 76, no. 2, p. 186-195

Publication date2018

Abstract

To determine the existence of autoantibodies against apolipoprotein A-1 (anti-apoA-1 IgG) in HIV patients and explore their association with biological features of HIV infection and different inflammatory biomarkers. We also evaluated their impact on CD4+ lymphocytes survival.

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Citation (ISO format)

SATTA POSCHUNG, Nathalie et al. Anti-apolipoprotein A-1 autoantibodies are associated with immunodeficiency and systemic inflammation in HIV patients. In: Journal of Infection, 2018, vol. 76, n° 2, p. 186–195. doi: 10.1016/j.jinf.2017.11.008

Article (Published version)

Identifiers

PID : unige:108541
DOI : 10.1016/j.jinf.2017.11.008
PMID : 29198606

Journal ISSN0163-4453

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Anti-apolipoprotein A-1 autoantibodies are associated with immunodeficiency and systemic inflammation in HIV patients

To determine the existence of autoantibodies against apolipoprotein A-1 (anti-apoA-1 IgG) in HIV patients and explore their association with biological features of HIV infection and different inflammatory biomarkers. We also evaluated their impact on CD4+ lymphocytes survival.

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