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Title

Autoantibody to apolipoprotein A-1 in hepatitis C virus infection: a role in atherosclerosis?
Authors
Bridge, Simon H
Pagano, Sabrina
Jones, Meleri
Foster, Graham R
Neely, Dermot
Vuilleumier, Nicolas
Bassendine, Margaret F
Published in Hepatology International. 2018, vol. 12, no. 1, p. 17-25
Abstract One to three per cent of the world's population has hepatitis C virus (HCV) infection, which is not only a major cause of liver disease and cancer but also associated with an increased risk of atherosclerosis, despite an ostensibly favourable lipid profile. Autoantibodies are frequent in HCV infection and emerging evidence shows that autoantibodies could be valuable for cardiovascular disease (CVD) risk stratification. This study investigated a novel independent biomarker of CVD, autoantibodies to apolipoprotein A-1 (anti-apoA-1 IgG) and lipids in patients with chronic HCV before, during and after direct-acting anti-viral (DAA) therapy.
Identifiers
PMID: 29423541
Full text
Article (Published version) (764 Kb) - public document Free access
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine
Faculté de médecine / Section de médecine fondamentale / Département de biologie structurale et bioinformatique
Research group Chimie et protéomique clinique (270)
Citation
(ISO format) 		BRIDGE, Simon H et al. Autoantibody to apolipoprotein A-1 in hepatitis C virus infection: a role in atherosclerosis?. In: Hepatology International, 2018, vol. 12, n° 1, p. 17-25. doi: 10.1007/s12072-018-9842-5 https://archive-ouverte.unige.ch/unige:108516

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Deposited on : 2018-09-26

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