Quantitative Analysis of Heterogeneous [18F]FDG Static (SUV) vs. Patlak (Ki) Whole-body PET Imaging Using Different Segmentation Methods: a Simulation Study

Zhuang, Mingzan; Karakatsanis, Nicolas A; Dierckx, Rudi A J O; Zaidi, Habib

doi:10.1007/s11307-018-1241-8

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Title		Quantitative Analysis of Heterogeneous [18F]FDG Static (SUV) vs. Patlak (Ki) Whole-body PET Imaging Using Different Segmentation Methods: a Simulation Study
Authors		Zhuang, Mingzan Karakatsanis, Nicolas A Dierckx, Rudi A J O Zaidi, Habib
Published in		Molecular Imaging and Biology. 2019, vol. 21, no. 2, p. 317-327
Abstract		Whole-body (WB) dynamic positron emission tomography (PET) enables imaging of highly quantitative physiological uptake parameters beyond the standardized uptake value (SUV). We present a novel dynamic WB anthropomorphic PET simulation framework to assess the potential of 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) net uptake rate constant (Ki) imaging in characterizing tumor heterogeneity.
Keywords		Heterogeneity — PET — Parametric imaging — Segmentation — Whole-body
Identifiers		DOI: 10.1007/s11307-018-1241-8 PMID: 29956119
Note		Merci de mettre à jour également le fichier pdf disponible sur: http://www.hcuge.ch/~pinlab/pdf/MIB2019.pdf
Full text		Article (Published version) (1.2 MB) - Free access Other version: http://www.hcuge.ch/~pinlab/pdf/MIB2019.pdf
Structures		Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research group		Imagerie Médicale (TEP et TEMP) (542)
Project		FNS: SNRF 320030_176052
Citation (ISO format)		ZHUANG, Mingzan et al. Quantitative Analysis of Heterogeneous [18F]FDG Static (SUV) vs. Patlak (Ki) Whole-body PET Imaging Using Different Segmentation Methods: a Simulation Study. In: Molecular Imaging and Biology, 2019, vol. 21, n° 2, p. 317-327. doi: 10.1007/s11307-018-1241-8 https://archive-ouverte.unige.ch/unige:108513