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Scientific article
Open access
English

Quantitative Analysis of Heterogeneous [18F]FDG Static (SUV) vs. Patlak (Ki) Whole-body PET Imaging Using Different Segmentation Methods: a Simulation Study

Published inMolecular Imaging and Biology, vol. 21, no. 2, p. 317-327
Publication date2019
Abstract

Whole-body (WB) dynamic positron emission tomography (PET) enables imaging of highly quantitative physiological uptake parameters beyond the standardized uptake value (SUV). We present a novel dynamic WB anthropomorphic PET simulation framework to assess the potential of 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) net uptake rate constant (Ki) imaging in characterizing tumor heterogeneity.

Keywords
  • Heterogeneity
  • PET
  • Parametric imaging
  • Segmentation
  • Whole-body
NoteMerci de mettre à jour également le fichier pdf disponible sur:http://www.hcuge.ch/~pinlab/pdf/MIB2019.pdf
Funding
  • Swiss National Science Foundation - SNRF 320030_176052
Citation (ISO format)
ZHUANG, Mingzan et al. Quantitative Analysis of Heterogeneous [18F]FDG Static (SUV) vs. Patlak (Ki) Whole-body PET Imaging Using Different Segmentation Methods: a Simulation Study. In: Molecular Imaging and Biology, 2019, vol. 21, n° 2, p. 317–327. doi: 10.1007/s11307-018-1241-8
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Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal1536-1632
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