UNIGE document Scientific Article
previous document  unige:108168  next document
add to browser collection
Title

Novel Natural Products for Healthy Ageing from the Mediterranean Diet and Food Plants of Other Global Sources-The MediHealth Project

Authors
Waltenberger, Birgit
Halabalaki, Maria
Schwaiger, Stefan
Adamopoulos, Nicolas
Allouche, Noureddine
Fiebich, Bernd L
Hermans, Nina
Jansen-Dürr, Pidder
show hidden authors show all authors [1 - 19]
Published in Molecules. 2018, vol. 23, no. 5
Abstract There is a rapid increase in the percentage of elderly people in Europe. Consequently, the prevalence of age-related diseases will also significantly increase. Therefore, the main goal of MediHealth, an international research project, is to introduce a novel approach for the discovery of active agents of food plants from the Mediterranean diet and other global sources that promote healthy ageing. To achieve this goal, a series of plants from the Mediterranean diet and food plants from other origins are carefully selected and subjected to in silico, cell-based, in vivo (fly and mouse models), and metabolism analyses. Advanced analytical techniques complement the bio-evaluation process for the efficient isolation and identification of the bioactive plant constituents. Furthermore, pharmacological profiling of bioactive natural products, as well as the identification and synthesis of their metabolites, is carried out. Finally, optimization studies are performed in order to proceed to the development of innovative nutraceuticals, dietary supplements or herbal medicinal products. The project is based on an exchange of researchers between nine universities and four companies from European and non-European countries, exploiting the existing complementary multidisciplinary expertise. Herein, the unique and novel approach of this interdisciplinary project is presented.
Identifiers
PMID: 29734769
Full text
Article (Published version) (675 Kb) - public document Free access
Structures
Research group Phytochimie et produits naturels bioactifs
Citation
(ISO format)
WALTENBERGER, Birgit et al. Novel Natural Products for Healthy Ageing from the Mediterranean Diet and Food Plants of Other Global Sources-The MediHealth Project. In: Molecules, 2018, vol. 23, n° 5. https://archive-ouverte.unige.ch/unige:108168

24 hits

10 downloads

Update

Deposited on : 2018-09-21

Export document
Format :
Citation style :