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Scientific article
Letter
English

An antifungal naphthoquinone, xanthones and secoiridoids from Swertia calycina

ContributorsRodriguez, S; Wolfender, Jean-Luc; Hakizamungu, E; Hostettmann, K
Published inPlanta Medica, vol. 61, no. 4, p. 362-364
Publication date1995
Abstract

A chemical and biological screening of 25 species of the Gentianaceae family has been undertaken. Both methanolic and dichloromethane extracts of Swertia calycina exhibited a strong antifungal activity against Cladosporium cucumerinum and Candida albicans. The compound responsible for this activity has been isolated and identified as 2-methoxy-1,4-naphthoquinone. It is the first naphthoquinone to be described in Gentianaceae species. LC-UV and LC-TSP-MS analysis of the crude extracts of Swertia calycina also allowed on-line identification of six known xanthones and secoiridoids.

Keywords
  • Antifungal Agents/isolation & purification/pharmacology
  • Chromatography, High Pressure Liquid
  • Glucosides/isolation & purification/pharmacology
  • Iridoid Glucosides
  • Iridoids
  • Mass Spectrometry
  • Microbial Sensitivity Tests
  • Naphthoquinones/isolation & purification/pharmacology
  • Plant Extracts
  • Pyrans/isolation & purification/pharmacology
  • Rwanda
Affiliation entities Not a UNIGE publication
Citation (ISO format)
RODRIGUEZ, S et al. An antifungal naphthoquinone, xanthones and secoiridoids from Swertia calycina. In: Planta Medica, 1995, vol. 61, n° 4, p. 362–364. doi: 10.1055/s-2006-958102
Identifiers
Journal ISSN0032-0943
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