An antifungal naphthoquinone, xanthones and secoiridoids from Swertia calycina
|Published in||Planta Medica. 1995, vol. 61, no. 4, p. 362-364|
|Abstract||A chemical and biological screening of 25 species of the Gentianaceae family has been undertaken. Both methanolic and dichloromethane extracts of Swertia calycina exhibited a strong antifungal activity against Cladosporium cucumerinum and Candida albicans. The compound responsible for this activity has been isolated and identified as 2-methoxy-1,4-naphthoquinone. It is the first naphthoquinone to be described in Gentianaceae species. LC-UV and LC-TSP-MS analysis of the crude extracts of Swertia calycina also allowed on-line identification of six known xanthones and secoiridoids.|
|Keywords||Antifungal Agents/isolation & purification/pharmacology — Chromatography, High Pressure Liquid — Glucosides/isolation & purification/pharmacology — Iridoid Glucosides — Iridoids — Mass Spectrometry — Microbial Sensitivity Tests — Naphthoquinones/isolation & purification/pharmacology — Plant Extracts — Pyrans/isolation & purification/pharmacology — Rwanda|
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|RODRIGUEZ, S et al. An antifungal naphthoquinone, xanthones and secoiridoids from Swertia calycina. In: Planta Medica, 1995, vol. 61, n° 4, p. 362-364. doi: 10.1055/s-2006-958102 https://archive-ouverte.unige.ch/unige:108158|