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Antifungal and antibacterial chalcones from Myrica serrata

Gafner, S
Mavi, S
Hostettmann, K
Published in Planta Medica. 1996, vol. 62, no. 1, p. 67-69
Abstract The dichloromethane extract of the leaves of Myrica serrata inhibits growth of Cladosporium cucumerinum, Bacillus subtilis, and Escherichia coli on TLC plates. Activity-guided fractionation led the isolation of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone (1), 2',4'-dihydroxy-6'-methoxy-5'-methylchalcone (aurentiacin A) (2), 2',6'-dihydroxy-4'-methoxy-3',5'-dimethyldihydrochalcone (3), 2'-hydroxy-4',6'-dimethoxy-3'-methyldihydrochalcone (4), and 2', 6'-dihydroxy-4'-methoxy-3'-methyldihydrochalcone (5). In addition, the flavanones demethoxymatteucinol (6) and cryptostrobin (7) were also identified.
Keywords Anti-Bacterial AgentsAnti-Infective Agents/chemistry/isolation & purification/pharmacologyAntifungal Agents/chemistry/isolation & purification/pharmacologyBacillus subtilis/drug effectsCandida albicans/drug effectsChalcone/chemistry/isolation & purification/pharmacologyCladosporium/drug effectsEscherichia coli/drug effectsMagnetic Resonance SpectroscopyMicrobial Sensitivity Tests
PMID: 8720393
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GAFNER, S et al. Antifungal and antibacterial chalcones from Myrica serrata. In: Planta Medica, 1996, vol. 62, n° 1, p. 67-69. doi: 10.1055/s-2006-957804

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