UNIGE document Scientific Article
previous document  unige:107412  next document
add to browser collection
Title

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology

Authors
Ripperger, Tim
Published in American Journal of Medical Genetics. A. 2017, vol. 173, no. 4, p. 1017-1037
Abstract Heritable predisposition is an important cause of cancer in children and adolescents. Although a large number of cancer predisposition genes and their associated syndromes and malignancies have already been described, it appears likely that there are more pediatric cancer patients in whom heritable cancer predisposition syndromes have yet to be recognized. In a consensus meeting in the beginning of 2016, we convened experts in Human Genetics and Pediatric Hematology/Oncology to review the available data, to categorize the large amount of information, and to develop recommendations regarding when a cancer predisposition syndrome should be suspected in a young oncology patient. This review summarizes the current knowledge of cancer predisposition syndromes in pediatric oncology and provides essential information on clinical situations in which a childhood cancer predisposition syndrome should be suspected.
Keywords AdolescentChildFocus Groups/methodsGene ExpressionGenetic Counseling/ethicsGenetic Predisposition to DiseaseGenetic Testing/methodsGeneticsMedical/history/instrumentation/methodsHematologic Neoplasms/diagnosis/genetics/pathologyHistory21st CenturyHumansMutationNeoplasm Proteins/geneticsNeoplasms/diagnosis/genetics/pathologySocietiesMedical/historySyndrome
Identifiers
PMID: 28168833
Full text
Article (Published version) (288 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Plateforme d'oncologie et d'hématologie pédiatrique (907)
Citation
(ISO format)
RIPPERGER, Tim, VON BUEREN, André. Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology. In: American Journal of Medical Genetics. A, 2017, vol. 173, n° 4, p. 1017-1037. https://archive-ouverte.unige.ch/unige:107412

67 hits

2 downloads

Update

Deposited on : 2018-09-04

Export document
Format :
Citation style :