In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case

Merat, Rastine; Boehncke, Wolf-Henning; Kaya, Guerkan

doi:10.5826/dpc.0702a10

Scientific article

English

In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case

Contributors

Merat, Rastine

; Boehncke, Wolf-Henning; Kaya, Guerkan

Published in

Dermatology Parctical and Conceptual, vol. 7, no. 2, p. 47-49

Publication date

2017

Abstract

Complete response can be difficult to assess after isolated limb perfusion (ILP) for metastatic in-transit melanoma, especially when numerous and unresectable post-necrotic persisting pigmented lesions occur. These residual lesions are mainly seen in the more superficial and pigmented types of metastatic disease and correspond to the residual melanophage granuloma that persists after tumor tissues undergo complete necrosis. Reflectance confocal microscopy (RCM) is a non-invasive technique that allows the exploration of the superficial dermis. Here, we present the case of a patient in whom numerous post-ILP limb residual pigmented lesions were explored using combined RCM and histological examination of sample lesions and could be characterized as non-active. This approach allowed us to avoid additional excisions.

UNIGE affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

UNIGE research groups

Inflammation cutanée (919)

Citation (ISO format)

MERAT, Rastine, BOEHNCKE, Wolf-Henning, KAYA, Guerkan. In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case. In: Dermatology Parctical and Conceptual, 2017, vol. 7, n° 2, p. 47–49. doi: 10.5826/dpc.0702a10

Article (Published version)

Identifiers

PID : unige:106965
DOI : 10.5826/dpc.0702a10
PMID : 28515994

Journal ISSN

2160-9381

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09/08/2018 15:13:00

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24/01/2025 16:02:38

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24/01/2025 16:02:38

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24/01/2025 16:08:52

In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case

Contributors

Published in

Publication date

Abstract

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

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Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation