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The Effect of Neoadjuvant Androgen Deprivation Therapy on Tumor Hypoxia in High-Grade Prostate Cancer: An 18F-MISO PET-MRI Study

Publication date2018
Abstract

Tumor hypoxia is associated with radioresistance and poor prognosis after radiation therapy for prostate cancer (PCa). In this prospective pilot study, we assessed the ability of 18F-misonidazole (18F-MISO) positron emission tomography (PET)-magnetic resonance imaging (MRI) to detect hypoxia in high-grade PCa patients who were candidates for curative radiation therapy, and we evaluated 18F-MISO PET-MRI modulation after 3 months of neoadjuvant androgen deprivation therapy (nADT).

Citation (ISO format)
MAINTA, Ismini Charis et al. The Effect of Neoadjuvant Androgen Deprivation Therapy on Tumor Hypoxia in High-Grade Prostate Cancer: An 18F-MISO PET-MRI Study. In: International Journal of Radiation Oncology, Biology, Physics, 2018. doi: 10.1016/j.ijrobp.2018.02.170
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ISSN of the journal0360-3016
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Creation06/18/2018 3:22:00 PM
First validation06/18/2018 3:22:00 PM
Update time03/15/2023 8:27:41 AM
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