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Title

Non-Phosphorylated Tau as a Potential Biomarker of Alzheimer's Disease: Analytical and Diagnostic Characterization

Authors
Lewczuk, Piotr
Lelental, Natalia
Lachmann, Ingolf
Holzer, Max
Flach, Katharina
Brandner, Sebastian
Engelborghs, Sebastiaan
Teunissen, Charlotte E
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Published in Journal of Alzheimer's Disease. 2017, vol. 55, no. 1, p. 159-170
Abstract Virtually nothing is known about a potential diagnostic role of non-phospho-epitopes of Tau (Non-P-Tau) in cerebrospinal fluid (CSF).
Keywords AgedAlzheimer Disease/cerebrospinal fluidAnimalsBiomarkers/cerebrospinal fluidCells, CulturedCognitive Dysfunction/cerebrospinal fluidEnzyme-Linked Immunosorbent Assay/methodsEpitope MappingFemaleHumansImmunoglobulin GMaleMice, Inbred BALB CPhosphorylationProtein StabilityReproducibility of ResultsSensitivity and SpecificitySpecimen Handling/methodsTemperaturetau Proteins/cerebrospinal fluid/genetics
Identifiers
PMID: 27662295
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Article (Published version) (604 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Research group Neuropsychiatrie et Biomarqueurs de la maladie d'Alzheimer (991)
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LEWCZUK, Piotr et al. Non-Phosphorylated Tau as a Potential Biomarker of Alzheimer's Disease: Analytical and Diagnostic Characterization. In: Journal of Alzheimer's Disease, 2017, vol. 55, n° 1, p. 159-170. https://archive-ouverte.unige.ch/unige:105992

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Deposited on : 2018-06-28

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