Scientific article

A cellular automata model of diffusion in aqueous systems

Published inJournal of pharmaceutical sciences, vol. 86, no. 7, p. 774-778
Publication date1997

A cellular automata model of a solute diffusing in water has been created and studied for the influential attributes. The results with this model are in agreement with experimental results; that is, that lipophilic solutes diffuse faster than do polar solutes. The model reveals that a solution composed of a relatively lipophilic solute permits a greater extent of diffusion of another solute. This observation is in agreement with the model showing a diffusion preference of a solute between two solutions made up of differing polarities. The solute diffuses farther into the lipophilic solution. A temperature-lipophilicity phase diagram shows the influence of these two attributes on the rate of diffusion. A model of diffusion through solutions containing stationary ingredients reveals a faster rate when the ingredient is lipophilic. We are led to a conclusion that the relative lipophilicity of solutes or stationary ingredients in a solution has a direct influence on the rates of diffusion of other solutes in their midst.

  • Diffusion
  • Models, Chemical
  • Solutions/*chemistry
  • Temperature
  • Water/*chemistry
Affiliation Not a UNIGE publication
Citation (ISO format)
KIER, Lemont B. et al. A cellular automata model of diffusion in aqueous systems. In: Journal of pharmaceutical sciences, 1997, vol. 86, n° 7, p. 774–778.
Updates (1)
ISSN of the journal0022-3549

Technical informations

Creation08/06/2010 1:48:37 PM
First validation08/06/2010 1:48:37 PM
Update time03/14/2023 4:00:17 PM
Status update03/14/2023 4:00:16 PM
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