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Title

Interaction between personality traits and cerebrospinal fluid biomarkers of Alzheimer's disease pathology modulates cognitive performance
Authors
Tautvydaite, Domile
Kukreja, Deepti
Antonietti, Jean-Philippe
Henry, Hugues
von Gunten, Armin
Popp, Julius
Published in Alzheimer's research & therapy. 2017, vol. 9, no. 1, 6
Abstract During adulthood, personality characteristics may contribute to the individual capacity to compensate the impact of developing cerebral Alzheimer's disease (AD) pathology on cognitive impairment in later life. In this study we aimed to investigate whether and how premorbid personality traits interact with cerebrospinal fluid (CSF) markers of AD pathology to predict cognitive performance in subjects with mild cognitive impairment or mild AD dementia and in participants with normal cognition.
Keywords Aged — Alzheimer Disease/cerebrospinal fluid/genetics/psychology — Apolipoprotein E4/genetics — Biomarkers/cerebrospinal fluid — Cognition/physiology — Cognitive Dysfunction/cerebrospinal fluid/genetics/psychology — Female — Humans — Male — Multivariate Analysis — Neuropsychological Tests — Personality/genetics/physiology — Regression Analysis — Retrospective Studies — Spinal Puncture
Identifiers
PMID: 28153054
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(ISO format) 		TAUTVYDAITE, Domile et al. Interaction between personality traits and cerebrospinal fluid biomarkers of Alzheimer's disease pathology modulates cognitive performance. In: Alzheimer's Research and Therapy, 2017, vol. 9, n° 1, p. 6. doi: 10.1186/s13195-017-0235-0 https://archive-ouverte.unige.ch/unige:105779

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Deposited on : 2018-06-20

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