Cognitive and motor performances are correlated with synchronized activity in functionally connected areas of the brain at resting state. This is measured by Functional Connectivity (FC). The nature of the link between FC and performance is still unclear. We proposed an approach that aimed to target FC with neurofeedback (NFB) and brain-computer interface (BCI) technology, based on a resting state network correlate of behavioral performance. We investigated the implication of FC on upper extremity motor function in chronic stroke patients in an alternate controlled cross-over study...